anti-cd20 antibody is effective in the patient with refractory amegakaryocytic thrombocytopenia, 25 months follow up.
نویسندگان
چکیده
amegakaryocytic thrombocytopenia (amt) is a rare cause of acquired thrombocytopenia. the pathogenesis and treatment of amt is not clearly known. here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. the patient did not respond to intravenous immunoglobulin, cyclosporine or high dose prednisone. after the treatment with anti-cd20 antibody (rituximab), the patient's clinical symptoms and platelet counts improved.
منابع مشابه
Anti-CD20 Antibody is Effective in the Patient with Refractory Amegakaryocytic Thrombocytopenia, 25 Months Follow up
Amegakaryocytic thrombocytopenia (AMT) is a rare cause of acquired thrombocytopenia. The pathogenesis and treatment of AMT is not clearly known. Here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. The patient did not respond to intravenous immunoglob...
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عنوان ژورنال:
international journal of hematology-oncology and stem cell researchجلد ۸، شماره ۲، صفحات ۴۱-۴۴
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